Mmetụta Nchedo nkeMicroecology akpụkpọna Skin
Ọkpụkpụ sebaceous na-ezobe lipids, nke microorganisms metabolized na-emepụta ihe nkiri lipid emulsified. Ihe nkiri lipid ndị a nwere acid fatty n'efu, nke a makwaara dị ka ihe nkiri acid, nke nwere ike wepụ ihe ndị na-emerụ emerụ na akpụkpọ ahụ ma gbochie nje bacteria ndị mba ọzọ (na-agafe nje bacteria). , fungi na microorganisms pathogenic ndị ọzọ na-eto eto, ya mere, ọrụ mbụ nke ahịhịa anụ ahụ nkịtị bụ ihe nchebe dị mkpa.
Mbanye nke akpụkpọ ahụ na akụkụ ahụ, gụnyere ọsụsọ (ọsụsọ gland), gland sebaceous, na follicles ntutu, nwere ahịhịa nke ha pụrụ iche. Ọkpụkpụ sebaceous na-ejikọta ntutu isi ka ọ bụrụ akụkụ nke sebaceous follicular, nke na-ezobe ihe bara ụba nke lipid a na-akpọ sebum. Sebum bụ ihe nkiri nchebe hydrophobic nke na-echebe ma na-eme ka akpụkpọ ahụ na ntutu dị mma ma na-eme ihe dị ka ọta antibacterial. Sebaceous glands dịtụ hypoxic, na-akwado uto nke facultative anaerobic nje bacteria dị ka.P. ihe otutu, nke nwere P. acnes lipase nke na-eweda sebum, hydrolyzes triglycerides na sebum, na-ahapụkwa acid fatty free. Bacteria nwere ike ịrapagidesi ike na acids fatty free, nke na-enyere aka ịkọwa colonization nke sebaceous glands site P. acnes, na ndị a free fatty acids na-enyekwa aka na acidity nke elu akpụkpọ ahụ (pH nke 5). A na-egbochi ọtụtụ nje bacteria na-akpata ọrịa, dị ka Staphylococcus aureus na Streptococcus pyogenes, na gburugburu acidic ma si otú ahụ dị mma maka uto nke coagulase-negative staphylococci na coryneform bacteria. Otú ọ dị, nchichi nke akpụkpọ ahụ na-eme ka mmụba nke pH nke ga-akwado uto nke S. aureus na S. pyogenes. N'ihi na ụmụ mmadụ na-emepụta sebum triglycerides karịa anụmanụ ndị ọzọ, ọtụtụ P. acnes na-achịkwa akpụkpọ ahụ mmadụ.
Oge nzipu: Jun-27-2022
