Ihe ịchọ mma na-acha ọcha na metabolism pigmenti

Ihe ịchọ mma na-acha ọcha naAgba agbaMetabolism

Melanin anabolism na-ekewa n'ime oge dị iche iche.Ndị ọkà mmụta sayensị kwenyere na ọ ga-ekwe omume ịmụ ihe ndị na-acha ọcha na-arụ ọrụ maka oge metabolic dị iche iche.

(1) Oge mmalite nke njikọ melanin

① itinye aka na ntụgharị na / ma ọ bụ glycosylation nke tyrosinase;② Na-egbochi ndị na-achịkwa na nhazi nke tyrosinase;③ Njikwa tyrosinase mgbe emechara ya.

(2) Oge njikọ nke Melanin
Dị ka isi enzyme na enzyme na-ebelata ọnụego maka njikọ melanin, ndị na-emechi tyrosinase bụ isi nyocha na ntụziaka mmepe ugbu a.Ebe ọ bụ na ọtụtụ ihe na-acha ọcha dị ka phenol na catechol dị ka tyrosine na dopa, a na-ekewakarị ihe ndị na-acha ọcha na-ekpuchi anya dị ka ndị na-adịghị asọmpi ma ọ bụ ndị na-asọmpi tyrosinase.

(3) Oge ngwụcha nke njikọ melanin

① Na-egbochi mbufe melanosome;ihe nwere serine protease inhibitory mmetụta, dị ka rwj-50353, zere kpamkpam UBV-induced epidermal pigmentation;soybean trypsin inhibitor nwere mmetụta na-acha ọcha doro anya ma ọ nweghị mmetụta na nsị nke sel pigmenti;Niacinamide, nwere ike igbochi nnyefe nke melanocytes n'etiti melanocytes na keratinocytes;② Mgbasa nke Melanin na metabolism, α-hydroxy acid, acid fatty free na retinoic acid, na-akpali mmeghari ohuru nke cell ma kwalite melaninized keratinocytes nke mwepụ.

Ọ dị mma ịmara na nyocha na ntinye nke ihe ndị na-acha ọcha na-adabere na metabolism nke melanin dị n'elu adịghị mma maka mgbochi na ọgwụgwọ nke plaques senile.Ebe ọ bụ na usoro nhazi plaque senile metụtara nguzobe nke lipofuscin, a na-ejikarị ihe ndị na-arụ ọrụ antioxidative na-egbu oge ma gbanwee plaques senile.