Hormone na-agbada na afọ, gụnyere estrogen, testosterone, dehydroepiandrosterone sulfate, na hormone uto.Mmetụta nke homonụ na akpụkpọ ahụ dị ọtụtụ, gụnyere ụbara ọdịnaya nke collagen, ịba ụba akpụkpọ ahụ, yana mma akpụkpọ ahụ.N'ime ha, mmetụta nke estrogen na-apụta ìhè karị, ma usoro nke mmetụta ya na sel ka aghọtachaghị nke ọma.A na-enweta mmetụta nke estrogen na akpụkpọ ahụ site na keratinocytes nke epidermis, fibroblasts na melanocytes nke dermis, yana sel follicle ntutu na sebaceous glands.Mgbe ikike ụmụ nwanyị nwere imepụta estrogen na-ebelata, usoro ịka nká akpụkpọ ahụ na-eme ngwa ngwa.Enweghi ike nke estradiol hormone na-ebelata ọrụ nke basal oyi akwa nke epidermis ma na-ebelata njikọ nke collagen na eriri na-agbanwe agbanwe, ihe niile dị mkpa maka ịnọgide na-enwe ike ịdị mma akpụkpọ ahụ.Mbelata nke postmenopausal estrogen etoju ọ bụghị nanị na-eduga ná mbelata akpụkpọ collagen ọdịnaya, kamakwa metabolism nke dermal sel na-emetụta postmenopausal obere estrogen etoju, na mgbanwe ndị a nwere ike ngwa ngwa gbanwee site topically ngwa nke estrogen.Nnwale egosila na estrogen nke nwanyi nwere ike ime ka collagen dịkwuo elu, na-eme ka ọkpụkpụ anụ ahụ dịkwuo mma, na-echekwa mmiri akpụkpọ anụ na ọrụ mgbochi nke stratum corneum site n'ịba ụba acid glycosaminoglycans na hyaluronic acid, nke mere na akpụkpọ ahụ na-eme ka ọ dịkwuo mma.Enwere ike ịhụ na mbelata nke ọrụ usoro endocrine nke ahụ bụkwa otu n'ime ihe ndị dị mkpa na-emetụta usoro ịka nká akpụkpọ ahụ.
Mbelata ihe nzuzo sitere na pituitary, adrenal, na gonads na-enye aka na mgbanwe njirimara nke anụ ahụ na phenotype na omume omume metụtara ịka nká.Ọbara ọbara nke 17β-estradiol, dehydroepiandrosterone, progesterone, hormone na-eto eto, na ihe na-eme ka insulin na-eto eto na-agbadata (IGF) -M na-ebelata na afọ.Otú ọ dị, ọkwa nke hormone na-eto eto na IGF-I na ọbara nwoke na-ebelata nke ukwuu, na mbelata nke ọkwa hormone na ụfọdụ ndị mmadụ nwere ike ime n'oge ochie.Hormones nwere ike imetụta ụdị akpụkpọ ahụ na ọrụ, ike nke anụ ahụ, ọgwụgwọ, cortical lipogenesis, na metabolism anụ ahụ.Usoro ọgwụgwọ estrogen nwere ike igbochi menopause na ịka nká akpụkpọ anụ.
——”Skin Epiphysiology” Yinmao Dong, Laiji Ma, Chemical Industry Press
Ya mere, ka anyị na-etolite, uche anyị na ọnọdụ akpụkpọ ahụ kwesịrị iji nwayọọ nwayọọ na-abawanye.Anyị nwere ike iji ụfọdụ ọkachamaraakụrụngwa nyocha anụ ahụileba anya na ịkọ ọkwa nke akpụkpọ ahụ, buru amụma nsogbu akpụkpọ ahụ n'oge, ma na-arụsi ọrụ ike na ha.
Oge nzipu: Jan-05-2023
