Ihe kacha mkpa na-eme ka akpụkpọ ahụ kaa nká:
ọkụ UV, foto,
Pasent iri asaa nke ịka nká akpụkpọ ahụ na-esite na foto
Ọkụ UV na-emetụta collagen dị n'ahụ anyị, nke na-eme ka akpụkpọ ahụ dị ka okoro. Ọ bụrụ na collagen ebelata, akpụkpọ ahụ ga-enwe mbelata ike ọkpụkpụ, ịchagharị, adịghị ike, agba akpụkpọ ahụ na-adịghị mma, hyperpigmentation, agba na nsogbu akpụkpọ ahụ ndị ọzọ.
A na-ekewa obosara anyanwụ n'ime UVA na UVB. Radieshọn UVB nwere obere ogologo ebili mmiri ma nwee ike ịgba naanị elu akpụkpọ ahụ anyị ọkụ, enweghị ike ịbanye n'ime akpụkpọ ahụ miri emi; Otú ọ dị, radieshọn UVA nwere ogologo ebili mmiri ma nwee ike ịbanye n'ime iko ma banye n'ime akpụkpọ ahụ, na-emesịa mee ka collagen ghara ịdị ike ma na-eduga na mmepe nke wrinkles.
N'ikwu ya n'ụzọ dị mfe, UVA na-eduga n'ịka nká, UVB na-eduga n'ọkụ, ìhè ultraviolet nwekwara ike imebi DNA nke sel, belata ọrụ fibroblast, a na-egbochikwa njikọ collagen, na-eduga na mgbanwe mkpụrụ ndụ, ịka nká, na apoptosis. Ya mere, UV dị ebe niile, ma anwụ na-acha ma ọ bụ ígwé ojii, ịkwesịrị ịrụ ọrụ dị mma nke nchekwa anyanwụ.
Ihe nke abụọ kachasị mkpa na-eme ka akpụkpọ ahụ kaa nká
Radicals na-enweghị oxidative
Isi okwu maka free radicals bụ 'oxygen'. Anyị na-eku ume ihe dị ka pasent 98 ruo 99 nke oxygen oge ọ bụla anyị na-eku ume; a na-eji ya agba nri anyị na-eri ọkụ ma na-ewepụta obere molekul ka mkpụrụ ndụ anyị wee gbazee, ọ na-ewepụtakwa ike dị ukwuu iji mee ka akwara anyị rụọ ọrụ.
Mana ikekwe 1% ma ọ bụ 2% nke oxygen na-ahọrọ ụzọ dị iche ma dị ize ndụ, obere oxygen a, nke a na-akpọkarị free radicals, nke na-awakpo mkpụrụ ndụ anyị. Ka oge na-aga, mmebi a na-agbakọta ka oge na-aga.
Ihe kacha pụta ìhè bụ ihe ịrịba ama nke ịka nká nke na-apụta n'akpụkpọ ahụ. Ahụ anyị nwere usoro nchebe nke na-edozi mmebi nke sitere na radicals free, mana mgbe radicals free na-agbakọta ngwa ngwa karịa ka mkpụrụ ndụ ahụ nwere ike idozi ha, akpụkpọ ahụ na-aka nká nwayọ nwayọ.
Foto dị n'elu bụ ezigbo akpụkpọ ahụ nke ahụ anyị, ị nwere ike ịhụ nke ọma na elu epidermis gbara ọchịchịrị na ala dermis na-enwu ntakịrị, dermis bụ ebe anyị na-emepụta collagen, a na-akpọkwa mkpụrụ ndụ ndị na-emepụta collagen fibroblasts, nke bụ igwe na-emepụta collagen.
Fibroblast dị n'etiti foto a bụ fibroblast, ududo gbara ha gburugburu bụkwa collagen. Fibroblast na-emepụta collagen, akpụkpọ ahụ dị obere bụkwa njikọ collagen nke nwere akụkụ atọ ma jikọta nke ọma, yana fibroblast na-adọta eriri collagen nke ọma iji nye akpụkpọ ahụ dị obere udidi zuru oke ma dị ire ụtọ.
Na akpụkpọ ahụ ochie, fibroblasts na njikọ collagen n'etiti mmebi nke fibroblasts meworo agadi ga-ajụkarị ịbanye na collagen, ka oge na-aga, akpụkpọ ahụ malitekwara ịka nká, nke a bụ ihe anyị na-ekwukarị na akpụkpọ ahụ na-aka nká, kedu ka anyị si edozi oxidation nke akpụkpọ ahụ natara?
Na mgbakwunye na itinyekwu uche na ihe mkpuchi anyanwụ, anyị nwere ike iji ụfọdụ nwere vitamin A, vitamin E, ferulic acid, resveratrol na ihe ndị ọzọ dị na ngwaahịa nlekọta akpụkpọ ahụ; anyị nwekwara ike iri mkpụrụ osisi na akwụkwọ nri ndị nwere agba mara mma karịa, dịka tomato, tomato bara ụba na lycopene.
Ọ nwere ike ịmịkọrọ oxygen nke ọma ma gbochie nrụgide oxidative, ị nwekwara ike iri broccoli karịa, broccoli nwere ihe a na-akpọ mmanụ mustard glycosides, mgbe e risịrị ihe a, a ga-echekwa ha n'ime akpụkpọ ahụ, ka mkpụrụ ndụ akpụkpọ ahụ wee nwee ike ichebe onwe ha, mkpụrụ osisi na akwụkwọ nri ndị a nwere ike ịkwalite iguzogide sel megide ịka nká.
Ihe nke atọ kachasị mkpa na-eme ka akpụkpọ ahụ kaa nká
Glycine akpụkpọ ahụ
N'okwu ọkachamara, a na-akpọ Glycation mmeghachi omume glycosylation na-abụghị enzymatic ma ọ bụ mmeghachi omume Melad. Ụkpụrụ bụ na ibelata shuga na-ejikọ na protein ma ọ bụrụ na enweghị enzymes; ibelata shuga na-agbanwe nke ukwuu site na protein, na ibelata shuga na protein na-enweta oxidation ogologo oge, dehydrogenation, na mmeghachi omume nhazigharị, na-ebute mmepụta nke ngwaahịa njedebe glycosylation nke oge ikpeazụ, ma ọ bụ AGEs maka mkpụmkpụ.
AGEs bụ otu ihe mkpofu ndị na-adịghị agbanwe agbanwe, ndị na-acha odo odo-agba aja aja, ndị jikọtara ya na ha, ndị na-anaghị atụ egwu mbibi enzyme, ha bụkwa otu n'ime ihe ndị na-akpata ịka nká mmadụ. Ka anyị na-aka nká, AGEs na-agbakọta n'ime ahụ, na-eduga n'ịbawanye ike nke mgbidi dị n'ime arịa ọbara, enweghị nha nha na metabolism ọkpụkpụ na-eduga na osteoporosis, na mbibi nke collagen na eriri elastin na dermis na-eduga na ịka nká akpụkpọ ahụ. A chịkọtara ịka nká akpụkpọ ahụ nke glycation kpatara n'otu ahịrịokwu: shuga na-ebibi protein ndị dị mma ma na-agbanwe nhazi protein ndị na-eto eto ka ọ bụrụ nhazi protein ochie, na-eduga na ịka nká na mfu nke elasticity nke collagen na eriri elastic na dermis.
Oge ozi: Mee-29-2024
